UK perspective research landscape for offshore renewable energy and its role in delivering net zero

Acknowledgements This work was conducted within the Supergen Offshore Renewable Energy (ORE) Hub, a £9 Million programme 2018–2023 funded by Engineering and Physical Sciences Research Council (EPSRC) under grant no. EP/S000747/1.Peer reviewedPublisher PD

Divided national memories and EU crises: how Eurosceptic parties mobilize historical narratives

IN ENGLISH: Historical grievances of different political groups in the EU contributed to the rising opposition to “Brussels”. This opposition is often framed through memories that contest the official EU narrative of the peaceful and prosperous continental integration that was able to overcome the destructions of the two world wars and the Cold War divisions. Based on the analysis of the development of some of the most prominent Eurosceptic parties (le Front National, die Alternative für Deutschland, Syriza, Podemos, Fidesz, Prawo i Sprawiedliwość), it is argued that recent EU crises and especially their interpretations have been influenced by the legacies of some of the most important periods of twentieth-century European history. The legacy of the Second World War and its aftermath in two founding member states (France, Germany), the legacy of right-wing dictatorships in two Southern European member states (Greece, Spain) and the legacy of communist dictatorships in two Central and Eastern European member states (Hungary, Poland) still shape narratives and stances towards European integration. --------------- IN CROATIAN: Osjećaj povijesnih nepravdi kod različitih političkih grupa u EU doprinijeli su rastućem protivljenju Bruxellesu. To protivljenje se često iskazuje upotrebom sjećanja koja dovode u pitanje službeni EU narativ o mirnom i prosperitetnom kontinentu koji je uspio prevladati dva svjetska rata i hladnoratovske podjele. Na osnovi analize razvoja nekoliko najprominentnijih euroskeptičnih stranaka (le Front National, die Alternative für Deutschland, Syriza, Podemos, Fidesz, Prawo i Sprawiedliwość), tvrdi se da su na nedavne EU krize i posebno na njihove interpretacije utjecale ostavštine nekih od najznačajnijih razdoblja europske povijesti u 20. stoljeću. Ostavština Drugog svjetskog rata i njegove posljedice u dvije države osnivačice (Francuska, Italija), ostavština desničarskih diktatura u dvije zemlje Južne Europe (Grčka, Španjolska) i ostavština komunističkih diktatura u dvije zemlje Srednje i Istočne Europe (Mađarska, Poljska) još uvijek oblikuju narative i pozicioniranje prema europskoj integraciji

Endothelial dysfunction in the streptozotocin-induced diabetic apoE-deficient mouse

1. Endothelial dysfunction plays a role in the development of atherosclerosis and diabetes-associated vascular disease and, in the streptozotocin (STZ)-induced apoE-deficient diabetic mouse, we report that, when compared to the citrate (CIT)-treated nondiabetic apoE-deficient control, acetylcholine (Ach)-mediated endothelium-dependent relaxation was reduced in the small mesenteric arteries (SMA) and the plaque-prone regions of the aorta from the STZ-diabetic mouse. 2. In the SMA the component of Ach-mediated relaxation that was attributed to nitric oxide (NO) from STZ-treated diabetic apoE-deficient mice was enhanced; however, the endothelium-derived hyperpolarizing factor (EDHF)-mediated component was reduced. The EDHF component was assessed by determining the component of the Ach-mediated response that was resistant to the combination of the NO synthase (NOS) inhibitor N(ω)-nitro-L-arginine methyl ester, cyclooxygenase inhibitor, indomethacin, and soluble guanylate cyclase inhibitor, ODQ, and inhibited by the combination of the intermediate conductance K(Ca) (IK(Ca)) inhibitor TRAM-34 and the small-conductance K(Ca) (SK(Ca)) inhibitor apamin. 3. Endothelial NOS was increased but SK2, SK3 and connexin (Cx) 37 mRNA expressions were significantly (P<0.05) decreased in the SMA from STZ-treated apoE-deficient mice compared to the CIT-treated controls. There was no difference in the IK(Ca) expression or in Cx 40, 43 and 45 mRNA levels between STZ- and CIT-treated mice. 4. The microvasculature of STZ-induced apoE-deficient mice developed endothelial dysfunction, which may be linked to a decrease in the contribution of the EDHF component due to a decrease in SK2 and 3 and Cx 37 expression